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Src kinase as a mediator of convergent molecular abnormalities leading to NMDAR hypoactivity in schizophrenia

Numerous investigations support decreased glutamatergic signaling as a pathogenic mechanism of schizophrenia: yet molecular underpinnings for such dysregulation are largely unknown. In the postmortem dorsolateral prefrontal cortex, we found striking decreases in tyrosine phosphorylation of N-methyl-...

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Detalhes bibliográficos
Publicado no:Mol Psychiatry
Main Authors: Banerjee, Anamika, Wang, Hoau-Yan, Borgmann-Winter, Karin E., MacDonald, Mathew L., Kaprielian, Hagop, Stucky, Andres, Kvasic, Jessica, Egbujo, Chijioke, Ray, Rabindranath, Talbot, Konrad, Hemby, Scott E, Siegel, Steven J., Arnold, Steven E., Sleiman, Patrick, Chang, Xiao, Hakonarson, Hakon, Gur, Raquel E., Hahn, Chang-Gyu
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5156326/
https://ncbi.nlm.nih.gov/pubmed/25330739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mp.2014.115
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