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CNS-wide Sexually Dimorphic Induction of the Major Histocompatibility Complex 1 Pathway With Aging

The major histocompatibility complex I (MHCI) pathway, which canonically functions in innate immune viral antigen presentation and detection, is functionally pleiotropic in the central nervous system (CNS). Alternative roles include developmental synapse pruning, regulation of synaptic plasticity, a...

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Detalhes bibliográficos
Publicado no:J Gerontol A Biol Sci Med Sci
Main Authors: Mangold, Colleen A., Masser, Dustin R., Stanford, David R., Bixler, Georgina V., Pisupati, Aditya, Giles, Cory B., Wren, Jonathan D., Ford, Matthew M., Sonntag, William E., Freeman, Willard M.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5155655/
https://ncbi.nlm.nih.gov/pubmed/26786204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gerona/glv232
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