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CNS-wide Sexually Dimorphic Induction of the Major Histocompatibility Complex 1 Pathway With Aging
The major histocompatibility complex I (MHCI) pathway, which canonically functions in innate immune viral antigen presentation and detection, is functionally pleiotropic in the central nervous system (CNS). Alternative roles include developmental synapse pruning, regulation of synaptic plasticity, a...
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Publicado no: | J Gerontol A Biol Sci Med Sci |
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Main Authors: | , , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Oxford University Press
2017
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5155655/ https://ncbi.nlm.nih.gov/pubmed/26786204 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gerona/glv232 |
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