CNS-wide Sexually Dimorphic Induction of the Major Histocompatibility Complex 1 Pathway With Aging

The major histocompatibility complex I (MHCI) pathway, which canonically functions in innate immune viral antigen presentation and detection, is functionally pleiotropic in the central nervous system (CNS). Alternative roles include developmental synapse pruning, regulation of synaptic plasticity, a...

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Detalles Bibliográficos
Publicado en:J Gerontol A Biol Sci Med Sci
Autores principales: Mangold, Colleen A., Masser, Dustin R., Stanford, David R., Bixler, Georgina V., Pisupati, Aditya, Giles, Cory B., Wren, Jonathan D., Ford, Matthew M., Sonntag, William E., Freeman, Willard M.
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2017
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Original Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5155655/
https://ncbi.nlm.nih.gov/pubmed/26786204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gerona/glv232
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