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The cell-autonomous mechanisms underlying the activity of metformin as an anticancer drug
The biguanide drug metformin profoundly affects cell metabolism, causing an impairment of the cell energy balance and triggering a plethora of pleiotropic effects that vary depending on the cellular or environmental context. Interestingly, a decade ago, it was observed that metformin-treated diabeti...
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| Udgivet i: | Br J Cancer |
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| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5155371/ https://ncbi.nlm.nih.gov/pubmed/27875520 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2016.385 |
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