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Enhanced Anticancer Activity of PF-04691502, a Dual PI3K/mTOR Inhibitor, in Combination With VEGF siRNA Against Non–small-cell Lung Cancer

Lung cancer is the leading cause of cancer deaths in both men and women in the United States accounting for about 27% of all cancer deceases. In our effort to develop newer therapy for lung cancer, we evaluated the combinatory antitumor effect of siRNA targeting VEGF and the PI3K/mTOR dual inhibitor...

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Detalhes bibliográficos
Publicado no:Mol Ther Nucleic Acids
Main Authors: Espana-Serrano, Laura, Chougule, Mahavir B
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5155322/
https://ncbi.nlm.nih.gov/pubmed/27845769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mtna.2016.90
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