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Aerosol Delivery of siRNA to the Lungs. Part 1: Rationale for Gene Delivery Systems

This article reviews the pulmonary route of administration, aerosol delivery devices, characterization of pulmonary drug delivery systems, and discusses the rationale for inhaled delivery of siRNA. Diseases with known protein malfunctions may be mitigated through the use of siRNA therapeutics. The i...

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Dades bibliogràfiques
Publicat a:Kona
Autors principals: Youngren-Ortiz, Susanne R., Gandhi, Nishant S., España-Serrano, Laura, Chougule, Mahavir B.
Format: Artigo
Idioma:Inglês
Publicat: 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4829385/
https://ncbi.nlm.nih.gov/pubmed/27081214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14356/kona.2016014
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