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C5a/C5aR pathway is essential for up-regulating SphK1 expression through p38-MAPK activation in acute liver failure

AIM: To investigate the role of the complement 5a (C5a)/C5a receptor (C5aR) pathway in the pathogenesis of acute liver failure (ALF) in a mouse model. METHODS: BALB/c mice were randomly assigned to different groups, and intraperitoneal injections of lipopolysaccharide (LPS)/D-galactosamine (D-GalN)...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:World J Gastroenterol
मुख्य लेखकों: Lei, Yan-Chang, Lu, Chun-Lei, Chen, Ling, Ge, Ke, Yang, Ling-Ling, Li, Wen, Wu, Yuan-Hua
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Baishideng Publishing Group Inc 2016
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC5155174/
https://ncbi.nlm.nih.gov/pubmed/28028363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v22.i46.10148
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