The E3 ubiquitin ligase TRIM31 attenuates NLRP3 inflammasome activation by promoting proteasomal degradation of NLRP3

The NLRP3 inflammasome has a fundamental role in host defence against microbial pathogens and its deregulation may cause diverse inflammatory diseases. NLRP3 protein expression is a rate-limiting step for inflammasome activation, thus its expression must be tightly controlled to maintain immune home...

Descrición completa

Gardado en:
Detalles Bibliográficos
Publicado en:Nat Commun
Main Authors: Song, Hui, Liu, Bingyu, Huai, Wanwan, Yu, Zhongxia, Wang, Wenwen, Zhao, Jing, Han, Lihui, Jiang, Guosheng, Zhang, Lining, Gao, Chengjiang, Zhao, Wei
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2016
Assuntos:
Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5155141/
https://ncbi.nlm.nih.gov/pubmed/27929086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms13727
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares