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UAF1 deubiquitinase complexes facilitate NLRP3 inflammasome activation by promoting NLRP3 expression

NOD-like receptor protein 3 (NLRP3) detects microbial infections or endogenous danger signals and activates the NLRP3 inflammasome, which has important functions in host defense and contributes to the pathogenesis of inflammatory diseases, and thereby needs to be tightly controlled. Deubiquitination...

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書目詳細資料
發表在:Nat Commun
Main Authors: Song, Hui, Zhao, Chunyuan, Yu, Zhongxia, Li, Qizhao, Yan, Rongzhen, Qin, Ying, Jia, Mutian, Zhao, Wei
格式: Artigo
語言:Inglês
出版: Nature Publishing Group UK 2020
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7695691/
https://ncbi.nlm.nih.gov/pubmed/33247121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-19939-8
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