Tissue-specific programming of memory CD8 T cell subsets impacts protection against lethal respiratory virus infection

How tissue-specific anatomical distribution and phenotypic specialization are linked to protective efficacy of memory T cells against reinfection is unclear. Here, we show that lung environmental cues program recently recruited central-like memory cells with migratory potentials for their tissue-spe...

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Publicado en:J Exp Med
Autores principales: Abboud, Georges, Desai, Pritesh, Dastmalchi, Farhad, Stanfield, Jessica, Tahiliani, Vikas, Hutchinson, Tarun E., Salek-Ardakani, Shahram
Formato: Artigo
Lenguaje:Inglês
Publicado: The Rockefeller University Press 2016
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Research Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5154936/
https://ncbi.nlm.nih.gov/pubmed/27879287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20160167
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