Tissue-specific programming of memory CD8 T cell subsets impacts protection against lethal respiratory virus infection

How tissue-specific anatomical distribution and phenotypic specialization are linked to protective efficacy of memory T cells against reinfection is unclear. Here, we show that lung environmental cues program recently recruited central-like memory cells with migratory potentials for their tissue-spe...

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Vydáno v:J Exp Med
Hlavní autoři: Abboud, Georges, Desai, Pritesh, Dastmalchi, Farhad, Stanfield, Jessica, Tahiliani, Vikas, Hutchinson, Tarun E., Salek-Ardakani, Shahram
Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 2016
Témata:
Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5154936/
https://ncbi.nlm.nih.gov/pubmed/27879287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20160167
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