Lack of B Lymphocytes Enhances CD8 T Cell-Mediated Resistance against Respiratory Viral Infection but Compromises Memory Cell Formation

Following a respiratory virus infection, CXCR3(hi) CX3CR1(lo) and CXCR3(lo) CX3CR1(hi) CD8 T cells localize to different compartments within the lung and play an important role in host resistance, but mechanisms governing their optimal generation are poorly defined. We serendipitously found that B c...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Desai, Pritesh, Stanfield, Jessica, Tahiliani, Vikas, Abboud, Georges, Salek-Ardakani, Shahram
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2020
Assuntos:
Cellular Response to Infection
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7000969/
https://ncbi.nlm.nih.gov/pubmed/31723023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01877-19
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