Transcription Factor Bcl11b Controls Effector and Memory CD8 T cell Fate Decision and Function during Poxvirus Infection

CD8(+) T cells play an important role in host resistance to many viral infections, but the underlying transcriptional mechanisms governing their differentiation and functionality remain poorly defined. By using a highly virulent systemic and respiratory poxvirus infection in mice, we show that the t...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Abboud, Georges, Stanfield, Jessica, Tahiliani, Vikas, Desai, Pritesh, Hutchinson, Tarun E., Lorentsen, Kyle J., Cho, Jonathan J., Avram, Dorina, Salek-Ardakani, Shahram
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2016
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5061747/
https://ncbi.nlm.nih.gov/pubmed/27790219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2016.00425
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