Systemic toxoplasma infection triggers a long-term defect in the generation and function of naive T lymphocytes

Because antigen-stimulated naive T cells either die as effectors or enter the activated/memory pool, continuous egress of new T lymphocytes from thymus is essential for maintenance of peripheral immune homeostasis. Unexpectedly, we found that systemic infection with the protozoan Toxoplasma gondii t...

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Dades bibliogràfiques
Publicat a:J Exp Med
Autors principals: Kugler, David G., Flomerfelt, Francis A., Costa, Diego L., Laky, Karen, Kamenyeva, Olena, Mittelstadt, Paul R., Gress, Ronald E., Rosshart, Stephan P., Rehermann, Barbara, Ashwell, Jonathan D., Sher, Alan, Jankovic, Dragana
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 2016
Matèries:
Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5154934/
https://ncbi.nlm.nih.gov/pubmed/27849554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20151636
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