Systemic toxoplasma infection triggers a long-term defect in the generation and function of naive T lymphocytes

Because antigen-stimulated naive T cells either die as effectors or enter the activated/memory pool, continuous egress of new T lymphocytes from thymus is essential for maintenance of peripheral immune homeostasis. Unexpectedly, we found that systemic infection with the protozoan Toxoplasma gondii t...

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Vydáno v:J Exp Med
Hlavní autoři: Kugler, David G., Flomerfelt, Francis A., Costa, Diego L., Laky, Karen, Kamenyeva, Olena, Mittelstadt, Paul R., Gress, Ronald E., Rosshart, Stephan P., Rehermann, Barbara, Ashwell, Jonathan D., Sher, Alan, Jankovic, Dragana
Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 2016
Témata:
Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5154934/
https://ncbi.nlm.nih.gov/pubmed/27849554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20151636
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