Systemic toxoplasma infection triggers a long-term defect in the generation and function of naive T lymphocytes

Because antigen-stimulated naive T cells either die as effectors or enter the activated/memory pool, continuous egress of new T lymphocytes from thymus is essential for maintenance of peripheral immune homeostasis. Unexpectedly, we found that systemic infection with the protozoan Toxoplasma gondii t...

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Detalhes bibliográficos
Publicado no:J Exp Med
Main Authors: Kugler, David G., Flomerfelt, Francis A., Costa, Diego L., Laky, Karen, Kamenyeva, Olena, Mittelstadt, Paul R., Gress, Ronald E., Rosshart, Stephan P., Rehermann, Barbara, Ashwell, Jonathan D., Sher, Alan, Jankovic, Dragana
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2016
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5154934/
https://ncbi.nlm.nih.gov/pubmed/27849554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20151636
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