The CHRNA5/CHRNA3/CHRNB4 nicotinic receptor regulome: genomic architecture, regulatory variants, and clinical associations

Functionally related genes often cluster into a genome region under coordinated regulation, forming a local regulome. To understand regulation of the CHRNA5/CHRNA3/CHRNB4 nicotinic receptor gene cluster, we integrate large-scale RNA expression data (brain and peripheral) from GTEx (Genotype Tissue E...

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Bibliografiset tiedot
Julkaisussa:Hum Mutat
Päätekijät: Barrie, Elizabeth S., Hartmann, Katherine, Lee, Sung-Ha, Frater, John T., Seweryn, Michal, Wang, Danxin, Sadee, Wolfgang
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2016
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5154896/
https://ncbi.nlm.nih.gov/pubmed/27758088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/humu.23135
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