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Combined genetic influence of the nicotinic receptor gene cluster CHRNA5/A3/B4 on nicotine dependence
BACKGROUND: The CHRNA5/A3/B4 gene locus is associated with nicotine dependence and other smoking related disorders. While the non-synonymous CHRNA5 variant rs16969968 appears to be the main risk factor, linkage disequilibrium (LD) bins in the gene cluster carry frequent variants that regulate expres...
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| Vydáno v: | BMC Genomics |
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| Hlavní autoři: | , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
BioMed Central
2018
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6245894/ https://ncbi.nlm.nih.gov/pubmed/30453884 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-018-5219-3 |
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