Combined genetic influence of the nicotinic receptor gene cluster CHRNA5/A3/B4 on nicotine dependence

BACKGROUND: The CHRNA5/A3/B4 gene locus is associated with nicotine dependence and other smoking related disorders. While the non-synonymous CHRNA5 variant rs16969968 appears to be the main risk factor, linkage disequilibrium (LD) bins in the gene cluster carry frequent variants that regulate expres...

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Publicat a:BMC Genomics
Autors principals: Lee, Sung-Ha, Ahn, Woo-Young, Seweryn, Michał, Sadee, Wolfgang
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2018
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6245894/
https://ncbi.nlm.nih.gov/pubmed/30453884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-018-5219-3
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