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THE TrkA RECEPTOR MEDIATES EXPERIMENTAL THERMAL HYPERALGESIA PRODUCED BY NERVE GROWTH FACTOR : modulation by the p75 neurotrophin receptor

The p75 neurotrophin receptor (p75(NTR)) and its activation of the sphingomyelin signaling cascade are essential for mechanical hypersensitivity resulting from locally injected nerve growth factor (NGF). Here the role of the same effectors, and of the TrkA receptor, are evaluated for thermal hyperal...

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Vydáno v:Neuroscience
Hlavní autoři: Khodorova, Alla, Nicol, Grant D., Strichartz, Gary
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5154773/
https://ncbi.nlm.nih.gov/pubmed/27826102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2016.10.064
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