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Enantioselective Synthesis of Fluoro–Dihydroquinazolones and –Benzooxazinones by Fluorination-Initiated Asymmetric Cyclization Reactions

[Image: see text] Stereoselective synthesis of two fluorine-bearing drug-like scaffolds, dihydroquinazolone and benzooxazinone, has been accomplished through asymmetric fluorocyclization reactions initiated by the fluorination process. The reaction employs double axially chiral anionic phase-transfe...

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Detalhes bibliográficos
Publicado no:ACS Catal
Main Authors: Hiramatsu, Kenichi, Honjo, Takashi, Rauniyar, Vivek, Toste, F. Dean
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5154691/
https://ncbi.nlm.nih.gov/pubmed/27980875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acscatal.5b02182
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