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Genomics and CSF analyses implicate thyroid hormone in hippocampal sclerosis of aging
We report evidence of a novel pathogenetic mechanism in which thyroid hormone dysregulation contributes to dementia in elderly persons. Two single nucleotide polymorphisms (SNPs) on chromosome 12p12 were the initial foci of our study: rs704180 and rs73069071. These SNPs were identified by separate r...
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| Publicado no: | Acta Neuropathol |
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| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5154615/ https://ncbi.nlm.nih.gov/pubmed/27815632 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-016-1641-2 |
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