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ABCC9/SUR2 in the brain: implications for hippocampal sclerosis of aging and a potential therapeutic target

The ABCC9 gene and its polypeptide product, SUR2, are increasingly implicated in human neurologic disease, including prevalent diseases of the aged brain. SUR2 proteins are a component of the ATP-sensitive potassium (“K(ATP)”) channel, a metabolic sensor for stress and/or hypoxia that has been shown...

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Detalhes bibliográficos
Publicado no:Ageing Res Rev
Main Authors: Nelson, Peter T., Jicha, Gregory A., Wang, Wang-Xia, Ighodaro, Eseosa, Artiushin, Sergey, Nichols, Colin G., Fardo, David W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4661124/
https://ncbi.nlm.nih.gov/pubmed/26226329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.arr.2015.07.007
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