ABCC9 gene polymorphism is associated with hippocampal sclerosis of aging pathology

Hippocampal sclerosis of aging (HS-Aging) is a high-morbidity brain disease in the elderly but risk factors are largely unknown. We report the first genome-wide association study (GWAS) with HS-Aging pathology as an endophenotype. In collaboration with the Alzheimer’s Disease Genetics Consortium, da...

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Detalhes bibliográficos
Main Authors: Nelson, Peter T., Estus, Steven, Abner, Erin L., Parikh, Ishita, Malik, Manasi, Neltner, Janna H., Ighodaro, Eseosa, Wang, Wang-Xia, Wilfred, Bernard R., Wang, Li-San, Kukull, Walter A., Nandakumar, Kannabiran, Farman, Mark L., Poon, Wayne W., Corrada, Maria M., Kawas, Claudia H., Cribbs, David H., Bennett, David A., Schneider, Julie A., Larson, Eric B., Crane, Paul K., Valladares, Otto, Schmitt, Frederick A., Kryscio, Richard J., Jicha, Gregory A., Smith, Charles D., Scheff, Stephen W., Sonnen, Joshua A., Haines, Jonathan L., Pericak-Vance, Margaret A., Mayeux, Richard, Farrer, Lindsay A., Van Eldik, Linda J., Horbinski, Craig, Green, Robert C., Gearing, Marla, Poon, Leonard W., Kramer, Patricia L., Woltjer, Randall L., Montine, Thomas J., Partch, Amanda B., Rajic, Alexander J., Richmire, KatieRose, Monsell, Sarah E., Schellenberg, Gerard D., Fardo, David W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4113197/
https://ncbi.nlm.nih.gov/pubmed/24770881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-014-1282-2
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