Adaptive Immune Response Impairs the Efficacy of Autologous Transplantation of Engineered Stem Cells in Dystrophic Dogs

Duchenne muscular dystrophy is the most common genetic muscular dystrophy. It is caused by mutations in the dystrophin gene, leading to absence of muscular dystrophin and to progressive degeneration of skeletal muscle. We have demonstrated that the exon skipping method safely and efficiently brings...

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Detalhes bibliográficos
Publicado no:Mol Ther
Main Authors: Sitzia, Clementina, Farini, Andrea, Jardim, Luciana, Razini, Paola, Belicchi, Marzia, Cassinelli, Letizia, Villa, Chiara, Erratico, Silvia, Parolini, Daniele, Bella, Pamela, da Silva Bizario, Joao Carlos, Garcia, Luis, Dias-Baruffi, Marcelo, Meregalli, Mirella, Torrente, Yvan
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5154479/
https://ncbi.nlm.nih.gov/pubmed/27506452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2016.163
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