Adaptive Immune Response Impairs the Efficacy of Autologous Transplantation of Engineered Stem Cells in Dystrophic Dogs

Duchenne muscular dystrophy is the most common genetic muscular dystrophy. It is caused by mutations in the dystrophin gene, leading to absence of muscular dystrophin and to progressive degeneration of skeletal muscle. We have demonstrated that the exon skipping method safely and efficiently brings...

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Dettagli Bibliografici
Pubblicato in:Mol Ther
Autori principali: Sitzia, Clementina, Farini, Andrea, Jardim, Luciana, Razini, Paola, Belicchi, Marzia, Cassinelli, Letizia, Villa, Chiara, Erratico, Silvia, Parolini, Daniele, Bella, Pamela, da Silva Bizario, Joao Carlos, Garcia, Luis, Dias-Baruffi, Marcelo, Meregalli, Mirella, Torrente, Yvan
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2016
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5154479/
https://ncbi.nlm.nih.gov/pubmed/27506452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2016.163
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