Comparative Systems Analyses Reveal Molecular Signatures of Clinically tested Vaccine Adjuvants

A better understanding of the mechanisms of action of human adjuvants could inform a rational development of next generation vaccines for human use. Here, we exploited a genome wide transcriptomics analysis combined with a systems biology approach to determine the molecular signatures induced by fou...

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Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Olafsdottir, Thorunn A., Lindqvist, Madelene, Nookaew, Intawat, Andersen, Peter, Maertzdorf, Jeroen, Persson, Josefine, Christensen, Dennis, Zhang, Yuan, Anderson, Jenna, Khoomrung, Sakda, Sen, Partho, Agger, Else Marie, Coler, Rhea, Carter, Darrick, Meinke, Andreas, Rappuoli, Rino, Kaufmann, Stefan H. E., Reed, Steven G., Harandi, Ali M.
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2016
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5153655/
https://ncbi.nlm.nih.gov/pubmed/27958370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep39097
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