Comparative Systems Analyses Reveal Molecular Signatures of Clinically tested Vaccine Adjuvants

A better understanding of the mechanisms of action of human adjuvants could inform a rational development of next generation vaccines for human use. Here, we exploited a genome wide transcriptomics analysis combined with a systems biology approach to determine the molecular signatures induced by fou...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Olafsdottir, Thorunn A., Lindqvist, Madelene, Nookaew, Intawat, Andersen, Peter, Maertzdorf, Jeroen, Persson, Josefine, Christensen, Dennis, Zhang, Yuan, Anderson, Jenna, Khoomrung, Sakda, Sen, Partho, Agger, Else Marie, Coler, Rhea, Carter, Darrick, Meinke, Andreas, Rappuoli, Rino, Kaufmann, Stefan H. E., Reed, Steven G., Harandi, Ali M.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5153655/
https://ncbi.nlm.nih.gov/pubmed/27958370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep39097
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