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Metabolic profiling and compound-class identification reveal alterations in serum triglyceride levels in mice immunized with human vaccine adjuvant Alum

Alum has been widely used as an adjuvant for human vaccines; however, the impact of Alum on host metabolism remains largely unknown. Herein, we applied mass spectrometry (LCMS)-based metabolic and lipid profiling to monitor the effects of Alum adjuvant on mouse serum at 6, 24, 72 and 168 h post-vacc...

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Detalhes bibliográficos
Publicado no:J Proteome Res
Main Authors: Khoomrung, Sakda, Nookaew, Intawat, Sen, Partho, Olafsdottir, Thorunn A., Persson, Josefine, Moritz, Thomas, Andersen, Peter, Harandi, Ali M., Nielsen, Jens
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7735194/
https://ncbi.nlm.nih.gov/pubmed/31625748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jproteome.9b00517
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