Regional CAR-T cell infusions for peritoneal carcinomatosis are superior to systemic delivery

Metastatic spread of colorectal cancer (CRC) to the peritoneal cavity is common and difficult to treat, with many patients dying from malignant bowel obstruction. Chimeric antigen receptor T cell (CAR-T) immunotherapy has shown great promise, and we previously reported murine and phase I clinical st...

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Detalhes bibliográficos
Publicado no:Cancer Gene Ther
Main Authors: Katz, Steven, Point, Gary R., Cunetta, Marissa, Thorn, Mitchell, Guha, Prajna, Espat, N. Joseph, Boutros, Cherif, Hanna, Nader, Junghans, Richard P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5153580/
https://ncbi.nlm.nih.gov/pubmed/27080226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cgt.2016.14
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