Regional CAR-T cell infusions for peritoneal carcinomatosis are superior to systemic delivery

Metastatic spread of colorectal cancer (CRC) to the peritoneal cavity is common and difficult to treat, with many patients dying from malignant bowel obstruction. Chimeric antigen receptor T cell (CAR-T) immunotherapy has shown great promise, and we previously reported murine and phase I clinical st...

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Bibliografske podrobnosti
izdano v:Cancer Gene Ther
Main Authors: Katz, Steven, Point, Gary R., Cunetta, Marissa, Thorn, Mitchell, Guha, Prajna, Espat, N. Joseph, Boutros, Cherif, Hanna, Nader, Junghans, Richard P.
Format: Artigo
Jezik:Inglês
Izdano: 2016
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5153580/
https://ncbi.nlm.nih.gov/pubmed/27080226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cgt.2016.14
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