Regional CAR-T cell infusions for peritoneal carcinomatosis are superior to systemic delivery

Metastatic spread of colorectal cancer (CRC) to the peritoneal cavity is common and difficult to treat, with many patients dying from malignant bowel obstruction. Chimeric antigen receptor T cell (CAR-T) immunotherapy has shown great promise, and we previously reported murine and phase I clinical st...

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Vydáno v:Cancer Gene Ther
Hlavní autoři: Katz, Steven, Point, Gary R., Cunetta, Marissa, Thorn, Mitchell, Guha, Prajna, Espat, N. Joseph, Boutros, Cherif, Hanna, Nader, Junghans, Richard P.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5153580/
https://ncbi.nlm.nih.gov/pubmed/27080226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cgt.2016.14
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