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Endocytosis as a Mechanism for Tyrosine Kinase-dependent Suppression of a Voltage-gated Potassium Channel

The voltage-gated potassium channel Kv1.2 undergoes tyrosine phosphorylation-dependent suppression of its ionic current. However, little is known about the physical mechanism behind that process. We have found that the Kv1.2 alpha-subunit protein undergoes endocytosis in response to the same stimuli...

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Detalhes bibliográficos
Main Authors: Nesti, Edmund, Everill, Brian, Morielli, Anthony D.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC515342/
https://ncbi.nlm.nih.gov/pubmed/15215309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E03-11-0788
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