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Free Fatty Acids Modulate Thrombin Mediated Fibrin Generation Resulting in Less Stable Clots

Upon platelet activation, free fatty acids are released at the stage of thrombus formation, but their effects on fibrin formation are largely unexplored. Our objective was to characterize the kinetic effects of fatty acids on thrombin activity, as well as the structural and mechanical properties of...

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Publicat a:PLoS One
Autors principals: Tanka-Salamon, Anna, Komorowicz, Erzsébet, Szabó, László, Tenekedjiev, Kiril, Kolev, Krasimir
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5152833/
https://ncbi.nlm.nih.gov/pubmed/27942000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0167806
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