Genetic and methylation variation in the CYP2B6 gene is related to circulating p,p′-dde levels in a population-based sample

OBJECTIVES: Since the metabolism of the organochlorine pesticide dichlorodiphenyltrichloroethane (DDT) is not fully known in humans, we evaluated if circulating levels of a major breakdown product of DDT, p,p′-DDE, were related to genome-wide genetic and methylation variation in a population-based s...

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Veröffentlicht in:Environ Int
Hauptverfasser: Lind, Lars, Ng, Esther, Ingelsson, Erik, Lindgren, Cecilia, Salihovic, Samira, van Bavel, Bert, Mahajan, Anubha, Lampa, Erik, Morris, Andrew P., Lind, P. Monica
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier Science 2017
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Full Length Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5152752/
https://ncbi.nlm.nih.gov/pubmed/27839851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.envint.2016.11.010
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