Genetic variation in the CYP2B6 Gene is related to circulating 2,2’,4,4’-tetrabromodiphenyl ether (BDE-47) concentrations: an observational population-based study

BACKGROUND: Since human CYP2B6 has been identified as the major CYP enzyme involved in the metabolism of 2,2’,4,4’-tetrabromodiphenyl ether (BDE-47) and that human 2B6 is a highly polymorphic CYP, with known functional variants, we evaluated if circulating concentrations of a major brominated flame...

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Detalhes bibliográficos
Main Authors: Penell, Johanna, Lind, Lars, Fall, Tove, Syvänen, Anne-Christine, Axelsson, Tomas, Lundmark, Per, Morris, Andrew P, Lindgren, Cecilia, Mahajan, Anubha, Salihovic, Samira, van Bavel, Bert, Ingelsson, Erik, Lind, P Monica
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4024654/
https://ncbi.nlm.nih.gov/pubmed/24885815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-069X-13-34
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