Genetic variation in the CYP1A1 gene is related to circulating PCB118 levels in a population-based sample

Several of the polychlorinated biphenyls (PCBs), i.e. the dioxin-like PCBs, are known to induce the P450 enzymes CYP1A1, CYP1A2 and CYP1B1 by activating the aryl hydrocarbon receptor (Ah)-receptor. We evaluated if circulating levels of PCBs in a population sample were related to genetic variation in...

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Publicado no:Environ Res
Main Authors: Lind, Lars, Penell, Johanna, Syvänen, Anne-Christine, Axelsson, Tomas, Ingelsson, Erik, Morris, Andrew P., Lindgren, Cecilia, Salihovic, Samira, van Bavel, Bert, Lind, P. Monica
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5562272/
https://ncbi.nlm.nih.gov/pubmed/24926919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.envres.2014.05.017
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