A small molecule inhibitor of β-catenin/cyclic AMP response element-binding protein transcription

Inherited and somatic mutations in the adenomatous polyposis coli occur in most colon cancers, leading to activation of β-catenin-responsive genes. To identify small molecule antagonists of this pathway, we challenged transformed colorectal cells with a secondary structure-templated chemical library...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Emami, Katayoon H., Nguyen, Cu, Ma, Hong, Kim, Dae Hoon, Jeong, Kwang Won, Eguchi, Masakatsu, Moon, Randall T., Teo, Jia-Ling, Oh, Se Wong, Kim, Hak Yeop, Moon, Sung Hwan, Ha, Jong Ryul, Kahn, Michael
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2004
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC515116/
https://ncbi.nlm.nih.gov/pubmed/15314234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0404875101
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker