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Identification of a small-molecule ligand that activates the neuropeptide receptor GPR171 and increases food intake
Several neuropeptide systems in the hypothalamus, including neuropeptide Y and agouti-related protein (AgRP), control food intake. Peptides derived from proSAAS, a precursor implicated in the regulation of body weight, also control food intake. GPR171 is a heterotrimeric guanine nucleotide–binding p...
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| Publicado no: | Sci Signal |
|---|---|
| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5150984/ https://ncbi.nlm.nih.gov/pubmed/27245612 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.aac8035 |
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