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Identification of N-(2-Phenoxyethyl)imidazo[1,2-a]pyridine-3-carboxamides as New Antituberculosis Agents
[Image: see text] A series of imidazo[1,2-a]pyridine carboxamides (IPAs) bearing an N-(2-phenoxyethyl) moiety was designed and synthesized as new antitubercular agents. Seven 2,6-dimethyl IPAs demonstrated excellent in vitro activity (MIC: 0.025–0.054 μg/mL) against the drug susceptive H37Rv strain...
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| 出版年: | ACS Med Chem Lett |
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| 主要な著者: | , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Chemical
Society
2016
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| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5150680/ https://ncbi.nlm.nih.gov/pubmed/27994751 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.6b00330 |
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