Role of F-Box Protein βTrcp1 in Mammary Gland Development and Tumorigenesis

The F-box protein βTrcp1 controls the stability of several crucial regulators of proliferation and apoptosis, including certain inhibitors of the NF-κB family of transcription factors. Here we show that mammary glands of βTrcp1(−/−) female mice display a hypoplastic phenotype, whereas no effects on...

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Main Authors: Kudo, Yasusei, Guardavaccaro, Daniele, Santamaria, Patricia G., Koyama-Nasu, Ryo, Latres, Esther, Bronson, Roderick, Yamasaki, Lili, Pagano, Michele
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2004
主題:
Cell Growth and Development
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC515055/
https://ncbi.nlm.nih.gov/pubmed/15340078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.18.8184-8194.2004
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