Different Effects of CSA and CSB Deficiency on Sensitivity to Oxidative DNA Damage

Mutations in the CSA and CSB genes cause Cockayne syndrome, a rare inherited disorder characterized by UV sensitivity, severe neurological abnormalities, and progeriod symptoms. Both gene products function in the transcription-coupled repair (TCR) subpathway of nucleotide excision repair (NER), prov...

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Detalhes bibliográficos
Main Authors: de Waard, Harm, de Wit, Jan, Andressoo, Jaan-Olle, van Oostrom, Conny T. M., Riis, Bente, Weimann, Allan, Poulsen, Henrik E., van Steeg, Harry, Hoeijmakers, Jan H. J., van der Horst, Gijsbertus T. J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
DNA Dynamics and Chromosome Structure
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC515046/
https://ncbi.nlm.nih.gov/pubmed/15340056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.18.7941-7948.2004
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