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Atomistic insight into lipid translocation by a TMEM16 scramblase

The transmembrane protein 16 (TMEM16) family of membrane proteins includes both lipid scramblases and ion channels involved in olfaction, nociception, and blood coagulation. The crystal structure of the fungal Nectria haematococca TMEM16 (nhTMEM16) scramblase suggested a putative mechanism of lipid...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Bethel, Neville P., Grabe, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5150362/
https://ncbi.nlm.nih.gov/pubmed/27872308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1607574113
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