Dilated Cardiomyopathy Caused by Aberrant Endoplasmic Reticulum Quality Control in Mutant KDEL Receptor Transgenic Mice

Aberrant protein folding beyond the capacity of endoplasmic reticulum (ER) quality control leads to stress response in the ER. The Lys-Asp-Glu-Leu (KDEL) receptor, a retrieval receptor for ER chaperones in the early secretory pathway, contributes to ER quality control. To elucidate the function of t...

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Bibliographische Detailangaben
Hauptverfasser: Hamada, Hiromichi, Suzuki, Masashi, Yuasa, Shigeki, Mimura, Naoya, Shinozuka, Norihiro, Takada, Yuki, Suzuki, Misao, Nishino, Takashi, Nakaya, Haruaki, Koseki, Haruhiko, Aoe, Tomohiko
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2004
Schlagworte:
Mammalian Genetic Models with Minimal or Complex Phenotypes
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC515036/
https://ncbi.nlm.nih.gov/pubmed/15340063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.18.8007-8017.2004
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