Dilated Cardiomyopathy Caused by Aberrant Endoplasmic Reticulum Quality Control in Mutant KDEL Receptor Transgenic Mice

Aberrant protein folding beyond the capacity of endoplasmic reticulum (ER) quality control leads to stress response in the ER. The Lys-Asp-Glu-Leu (KDEL) receptor, a retrieval receptor for ER chaperones in the early secretory pathway, contributes to ER quality control. To elucidate the function of t...

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Autori principali: Hamada, Hiromichi, Suzuki, Masashi, Yuasa, Shigeki, Mimura, Naoya, Shinozuka, Norihiro, Takada, Yuki, Suzuki, Misao, Nishino, Takashi, Nakaya, Haruaki, Koseki, Haruhiko, Aoe, Tomohiko
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2004
Soggetti:
Mammalian Genetic Models with Minimal or Complex Phenotypes
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC515036/
https://ncbi.nlm.nih.gov/pubmed/15340063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.18.8007-8017.2004
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