Dilated Cardiomyopathy Caused by Aberrant Endoplasmic Reticulum Quality Control in Mutant KDEL Receptor Transgenic Mice

Aberrant protein folding beyond the capacity of endoplasmic reticulum (ER) quality control leads to stress response in the ER. The Lys-Asp-Glu-Leu (KDEL) receptor, a retrieval receptor for ER chaperones in the early secretory pathway, contributes to ER quality control. To elucidate the function of t...

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Autores principales: Hamada, Hiromichi, Suzuki, Masashi, Yuasa, Shigeki, Mimura, Naoya, Shinozuka, Norihiro, Takada, Yuki, Suzuki, Misao, Nishino, Takashi, Nakaya, Haruaki, Koseki, Haruhiko, Aoe, Tomohiko
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2004
Materias:
Mammalian Genetic Models with Minimal or Complex Phenotypes
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC515036/
https://ncbi.nlm.nih.gov/pubmed/15340063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.18.8007-8017.2004
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