A Consecutive Priming-Boosting Vaccination of Mice with Simian Immunodeficiency Virus (SIV) gag/pol DNA and Recombinant Vaccinia Virus Strain DIs Elicits Effective Anti-SIV Immunity

To evaluate immunity induced by a novel DNA prime-boost regimen, we constructed a DNA plasmid encoding the gag and pol genes from simian immunodeficiency virus (SIV) (SIVgag/pol DNA), in addition to a replication-deficient vaccinia virus strain DIs recombinant expressing SIV gag and pol genes (rDIsS...

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Bibliographic Details
Main Authors: Someya, Kenji, Xin, Ke-Qin, Matsuo, Kazuhiro, Okuda, Kenji, Yamamoto, Naoki, Honda, Mitsuo
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2004
Subjects:
Vaccines and Antiviral Agents
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC515009/
https://ncbi.nlm.nih.gov/pubmed/15331719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.18.9842-9853.2004
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