Immunization with a Modified Vaccinia Virus Expressing Simian Immunodeficiency Virus (SIV) Gag-Pol Primes for an Anamnestic Gag-Specific Cytotoxic T-Lymphocyte Response and Is Associated with Reduction of Viremia after SIV Challenge

The immunogenicity and protective efficacy of a modified vaccinia virus Ankara (MVA) recombinant expressing the simian immunodeficiency virus (SIV) Gag-Pol proteins (MVA-gag-pol) was explored in rhesus monkeys expressing the major histocompatibility complex (MHC) class I allele, MamuA*01. Macaques r...

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Autores principales: Seth, Aruna, Ourmanov, Ilnour, Schmitz, Jorn E., Kuroda, Marcelo J., Lifton, Michelle A., Nickerson, Christine E., Wyatt, Linda, Carroll, Miles, Moss, Bernard, Venzon, David, Letvin, Norman L., Hirsch, Vanessa M.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2000
Materias:
Vaccines and Antiviral Agents
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC111738/
https://ncbi.nlm.nih.gov/pubmed/10684264
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