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SIRT1/3 Activation by Resveratrol Attenuates Acute Kidney Injury in a Septic Rat Model

Sepsis often results in damage to multiple organ systems, possibly due to severe mitochondrial dysfunction. Two members of the sirtuin family, SIRT1 and SIRT3, have been implicated in the reversal of mitochondrial damage. The aim of this study was to determine the role of SIRT1/3 in acute kidney inj...

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Detalhes bibliográficos
Publicado no:Oxid Med Cell Longev
Main Authors: Xu, Siqi, Gao, Youguang, Zhang, Qin, Wei, Siwei, Chen, Zhongqing, Dai, Xingui, Zeng, Zhenhua, Zhao, Ke-seng
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5149703/
https://ncbi.nlm.nih.gov/pubmed/28003866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/7296092
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