SIRT1/3 Activation by Resveratrol Attenuates Acute Kidney Injury in a Septic Rat Model

Sepsis often results in damage to multiple organ systems, possibly due to severe mitochondrial dysfunction. Two members of the sirtuin family, SIRT1 and SIRT3, have been implicated in the reversal of mitochondrial damage. The aim of this study was to determine the role of SIRT1/3 in acute kidney inj...

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Bibliographische Detailangaben
Veröffentlicht in:Oxid Med Cell Longev
Hauptverfasser: Xu, Siqi, Gao, Youguang, Zhang, Qin, Wei, Siwei, Chen, Zhongqing, Dai, Xingui, Zeng, Zhenhua, Zhao, Ke-seng
Format: Artigo
Sprache:Inglês
Veröffentlicht: Hindawi Publishing Corporation 2016
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5149703/
https://ncbi.nlm.nih.gov/pubmed/28003866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/7296092
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