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Impact of the MICA-129Met/Val Dimorphism on NKG2D-Mediated Biological Functions and Disease Risks

The major histocompatibility complex (MHC) class I chain-related A (MICA) is the most polymorphic non-classical MHC class I gene in humans. It encodes a ligand for NKG2D (NK group 2, member D), an activating natural killer (NK) receptor that is expressed mainly on NK cells and CD8(+) T cells. The si...

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Bibliografiske detaljer
Udgivet i:Front Immunol
Main Authors: Isernhagen, Antje, Malzahn, Dörthe, Bickeböller, Heike, Dressel, Ralf
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5149524/
https://ncbi.nlm.nih.gov/pubmed/28018354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2016.00588
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