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IL-17 receptor signaling in the lung epithelium is required for mucosal chemokine gradients and pulmonary host defense against K. pneumoniae
The cytokine IL17, and signaling via its heterodimeric IL-17RA/IL-17RC receptor, is critical for host defense against extracellular bacterial and fungal pathogens. Polarized lung epithelial cells express IL-17RA and IL-17RC basolaterally. However, their contribution to IL-17-dependent pulmonary defe...
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| Gepubliceerd in: | Cell Host Microbe |
|---|---|
| Hoofdauteurs: | , , , , , , , , , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2016
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5149406/ https://ncbi.nlm.nih.gov/pubmed/27923703 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2016.10.003 |
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