Ethanol Impairs Mucosal Immunity against Streptococcus pneumoniae Infection by Disrupting Interleukin 17 Gene Expression

Acute ethanol intoxication suppresses the host immune responses against Streptococcus pneumoniae. As interleukin 17 (IL-17) is a critical cytokine in host defense against extracellular pathogens, including S. pneumoniae, we hypothesized that ethanol impairs mucosal immunity against this pathogen by...

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Udgivet i:Infect Immun
Main Authors: Trevejo-Nunez, Giraldina, Chen, Kong, Dufour, Jason P., Bagby, Gregory J., Horne, William T., Nelson, Steve, Kolls, Jay K.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2015
Fag:
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4399072/
https://ncbi.nlm.nih.gov/pubmed/25754201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.02869-14
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