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Concurrent versus individual binding of HuR and AUF1 to common labile target mRNAs

RNA-binding proteins HuR and AUF1 bind to many common AU-rich target mRNAs and exert opposing influence on target mRNA stability, but the functional interactions between HuR and AUF1 have not been systematically studied. Here, using common target RNAs encoding p21 and cyclin D1, we provide evidence...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Lal, Ashish, Mazan-Mamczarz, Krystyna, Kawai, Tomoko, Yang, Xiaoling, Martindale, Jennifer L, Gorospe, Myriam
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2004
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC514922/
https://ncbi.nlm.nih.gov/pubmed/15257295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600305
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